
Pinky and the Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility.

The characters later appeared in the series Pinky, Elmyra & the Brain, and have since returned to their roots as an Animaniacs skit in the 2020 revival of that series. It was later spun off as a series due to its popularity, with 66 episodes produced. The characters first appeared in 1993 as a recurring skit on Animaniacs. It was the first animated television series to be presented in Dolby Surround and the fourth collaboration of Steven Spielberg with his production company, Amblin Entertainment, and Warner Bros. Pinky and the Brain is an American animated television series that was created by Tom Ruegger that premiered on Kids' WB on September 9, 1995.
